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AURORA Risk Assessment Framework

Task 5.5 Implementation roadmap (click on a card to see current status)
Phase 1 · Hazard

📊 Qualitative Hazard Assessment

Polymer + chemical banding · exposure-driven prioritisation

🤰 Exposure Scenario 1

Foetus

Transplacental · plausibility filter

🍼 Exposure Scenario 2

Neonate

PP bottles · ageing emission

👶 Exposure Scenario 3

Infant

Crawling · pig‑pen effect

🧸 Exposure Scenario 4

Toddler

Dust ingestion · toy migration

Phase 3 · Dosimetry

⚙️ Probabilistic (Monte Carlo) Exposure Assessment

10k simulations · particle kinetics · gut & lung deposition

Phase 4 · Hazard

🧬 Particle characterisation

Zeta potential · chemical load · morphology

Output

📋 Risk characterisation

Low · Medium · High banding

Phase 5 · Routes

🧪 Exposure route expansion

Breast milk · pulmonary translocation · infant diet · toy particles · dermal

Phase 6 · Dosimetry

⚖️ Advanced dosimetry

Size‑dependent kinetics · agglomeration · mass/surface‑area metrics

Phase 7 · Hazard

🔬 Quantitative hazard integration

TRVs → MOEs · SCCWRP endpoints · multi‑endpoint profiles

Phase 8 · Uncertainty

📈 Uncertainty & Refinement

Uncertainty · pathway contributions · sensitivity · population‑level